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Stem cells


Glioblastoma Dervied Stem-like Cells: Molecular Characteristics & Treatment Response

We welcome you to a selection of talks from "Diagnosis and Therapeutic Discovery in Neuro-Oncology." We are honored to present to you a unique group of basic and clinical oncologists, who presented their current data in both clinical and basic research areas. The live program addressed cutting edge research in oncology. Thank you for participating in this self-study course.

 

Dr. Colman addresses the 'cancer stem cell hypothesis', which proposes that a subset of cells may initiate and maintain tumors like glioblastoma. Dr. Colman's research demonstrates that glioblastoma stem cell lines are genetically stable and recapitulate important features of the human disease.



Targeting The Notch Pathway In Stem-like Embryonal Brain Tumor Cells

We welcome you to a selection of talks from "Diagnosis and Therapeutic Discovery in Neuro-Oncology." We are honored to present to you a unique group of basic and clinical oncologists, who presented their current data in both clinical and basic research areas. The live program addressed cutting edge research in oncology. Thank you for participating in this self-study course.


Dr. Eberhart is investigating the effects of Notch pathway inhibition on medulloblastoma growth using pharmacological inhibitors of gamma-secretase.

Origins of Cancer Stem Cells

We welcome you to a selection of talks from the live symposium titled, From Discovery to Application: Biomarkers, Diagnostics, and Molecular Therapeutics in Cancer. We are honored to present to you many world leaders in science. The program addresses dramatic advances in translational oncology, including discussions of target discovery, target validation, and drug development. Thank you for participating in this self-study course.

 

Dr. Zon illustrates how his lab generated a transgenic zebrafish that is p53 deficient and expresses an activating BRAF mutation. These transgenic zebrafish develop melanomas that are transplantable, and these fish are being used to study cancer stem cells.



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