Thursday, December 7, 2006
1:00 pm Opening Remarks
Paul A. Bunn, Jr. M.D.
1:15 pm Keynote: Was the Oncogene Revolution a Setback for Clinical Oncology?
Tak W. Mak, Ph.D.
Session I – Animal Models and Imaging
Session Chair Dr. Andrew Thorburn
2:15 pm Real Time Imaging of Signal Transduction Modulators In Vivo
David Piwnica-Worms, M.D., Ph.D.
2:55 pm Magnetic Resonance to Assess Therapeutic Response
Natalie Serkova, Ph.D.
3:35 pm Break & Refreshments
3:50 pm Pharmacokinetic Modeling in Animal Models as a Tool in Therapeutic Development
Daniel L. Gustafson, Ph.D.
4:30 pm Role of Eicosanoids in PPARg in Lung Tumorigenesis
Raphael Nemenoff, Ph.D.
5:10 - 7:00 pm Poster Reception
7:00 pm Presentation of Poster Awards
7:10 pm Adjourn
Friday, December 8, 2006
8:30 am Opening Remarks
Session II – TRAIL-Mediated Pathways
Session Chair, Dr. Marileila Varella Garcia
8:45 am Sensitizing TRAIL-Resistant Tumors
Wafik El-Deiry, M.D.
9:25 am TRAIL Receptor Signaling by Receptor-Specific Agonists
Andrew Thorburn, Ph.D.
10:05 am Break & Refreshments
10:25 am SIX1 as a Modulator of TRAIL Response in Ovarian and Breast Cancer
Heide L. Ford, Ph.D.
11:05 am Clinical Application of TRAIL-based Agents
S. Gail Eckhardt, M.D.
11:45 am Complimentary Lunch
Session III – Tyrosine Kinase Receptors
Session Chair, Dr. S. Gail Eckhardt
1:00 pm Inhibition of IGF Receptors as Cancer Therapy
Douglas Yee, M.D.
1:40 pm EGF Receptor Endocytosis and Signaling
Alex Sorkin, M.D.
2:20 pm An In Vitro Screen for Radiation Sensitizers
Tin Tin Su, Ph.D.
3:00 pm Break & Refreshments
3:20 pm In Vivo Platform for Drug Development in Pancreatic Cancer
Manuel Hidalgo, Ph.D
4:00 pm Biomarkers for Patient Selection for EGFR Inhibitors
Paul A. Bunn, Jr. M.D.
4:40 pm Closing remarks & Adjourn
