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Hypoxia, Ischemia, and Inflammation:Statement of Educational NeedTissue hypoxia is an important component of many clinical pathologies. Cellular signaling pathways regulated by hypoxia have been defined over the last decade and have identified key mechanisms for regulating inflammatory responses both independently of, and in combination with, hypoxia. Understanding these pathways has the potential for identifying new therapies for major disease areas such as inflammation, cancer and stroke. This program will further our understanding of hypoxic responses and their interplay with established signaling pathways.
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