Hypoxia, Ischemia, and Inflammation:

PRELIMINARY AGENDA

 

Friday, November 7, 2008

 

8:00 am Registration and Breakfast

 

Session I – Hypoxia and Inflammation

Session Chair, Antonio Sica

 

9:00 am Introductory Remarks

Randall Johnson

 

9:05 am Thiol/Redox-mediated Hypoxia Sensor On The

VMDA-type Glutamate Receptor

Stuart Lipton

 

9:45 am NF-KB Signaling in Hypoxia

Cormac Taylor

 

10:25 am BioSymposia Young Investigator Award Presentation

 

10:35 am Break

 

10:55 am Tumor-associated Macrophages as a Therapeutic Target

Antonio Sica

 

11:35 am Role of Hypoxia in Inflammation-induced Tumor Progression

and Angiogenesis

Randall Johnson

 

12:15 pm BioSymposia Young Investigator Award Presentation

 

12:25 pm Lunch

 

Session II – Hypoxia in Inflammatory and Infectious Disease

Session Chair, Victor Nizet

 

1:30 pm HIF-1 and Innate Immune Defense to Bacterial Infection

Victor Nizet

 

2:10 pm New Insights into Hypoxia and Mucosal Inflammation

Sean Colgan

 

2:50 pm BioSymposia Young Investigator Award Presentation

 

3:00 pm Break

 

3:15 pm Effect of Hypoxia on the Function and Fate of Neutrophils

Edwin Chilvers

 

3:45 pm Dissecting Neutrophil Function and Lifespan in Hypoxia

Moira Whyte

 

4:15 pm Late-Breaking Abstract 

 

4:30 pm Presentation of the BioSymposia Young Investigator Travel Awards

 

4:45 pm Poster Reception

 

Saturday, November 8, 2008

 

7:30 – 8:30 am Breakfast

 

Session III – Ischemia and Angiogenesis

Session Chair, Ken Chien

 

8:30 am Opening Remarks

Moira Whyte

 

8:35 am Hypoxia-Inducible Factor Signaling in Tissue Fibrosis

Volker Haase

 

9:15 am ROS and HIF: An Emerging Liaison

Agnes Gorlach

 

9:55 am BioSymposia Young Investigator Award Presentation

 

10:05 am Break

 

10:25 am How To Make A Heart: Islet-1 Progenitors and Human

Models of Human Cardiovascular Disease

Ken Chien

 

11:10 am PHD Gene Inactivation Studies: From Oxygen Sensing

to Oxygen Delivery and Hypoxia Tolerance

Peter Carmeliet

 

11:55 am Lunch

 

Session IV – Metabolic Consequences and Therapeutic Targeting

Session Chair, William Kaelin, Jr.

 

1:00 pm Hypoxia-Driven Anti-inflammatory and Cancerous

Tissue-Protecting Pathways

Mikhail Sitkovsky 

 

1:40 pm Prolyl Hydroxylases as Therapeutic Targets in Cancer

and Ischemic Diseases

William Kaelin, Jr.

 

2:20 pm Macrophage Response to Hypoxia in Tumors: Role of

HIFs 1 and 2

Claire Lewis

 

2:50 pm Break

 

3:10 pm HIF Hydroxylases

Christopher Pugh

 

3:40 pm HIF Prolyl Hydroxylase Inhibitors: Novel Agents for the

Treatment of Anemia

Stephen Klaus

 

4:10 pm Keynote Lecture

Bruce Spiegelman 

 

5:10 pm Closing Remarks

 

5:15 pm Adjourn