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Tregs and Th17 Cells in Autoimmunity

Scientific Program

Tuesday, March 25, 2008

 

8:00 am Registration, Continental Breakfast

 

Session I – Induction of IL-17 Cells

Session Chair, David Hafler

 

9:00 am Opening Remarks

David Hafler

 

9:10 am

The Protective vs. Pathogenic Functions of Th17 Cells in Autoimmune Inflammation

Mandy McGeachy 

 

9:50 am Regulation and Function of Inflammatory T Cells

Chen Dong

 

10:30 am NMSS Junior Investigator Award Presentation

 

10:35 am Break

 

10:55 am Heterogeneity of Human Memory T Helper Cell Subsets

Federica Sallusto

 

11:35 am Regulation of Autoimmune Responses

David Hafler

 

12:15 pm NMSS Junior Investigator Award Presentation

 

12:20 pm Lunch

 

Session II – Relationship of Tregs and Th17 Cells

Session Chair, Vijay Kuchroo

 

1:30 p.m. The Reciprocal Relationship Between Tregs and Th17 Cells

Vijay Kuchroo

 

2:10 p.m. Controlling Treg versus Th17 Developmental Decisions

Casey Weaver

 

2:50 pm NMSS Junior Investigator Award Presentation

 

2:55 pm Break

 

3:15 pm Foxp3 Controls Treg/Th17 Differentiation

Steven Ziegler

 

3:55 pm The Anti-inflammatory Properties of IL-27

Chris Hunter

 

4:35 pm Presentation of the National Multiple Sclerosis Society Junior Investigator Travel Awards

 

4:45 pm Poster Reception

 

Wednesday, March 26, 2008

 

7:30 am Breakfast

 

Session III – Regulatory T Cells: Induction and Function

Session Chair, Fiona Powrie

 

8:30 am Opening Remarks

Vijay Kuchroo

 

8:40 am How do Tregs Control Organ-specific Autoimmune Disease?

Ethan Shevach

 

9:20 am Factors Controlling The Balance Between Effector and Regulatory

T Cells In The Gut 

Fiona Powrie

 

10:00 am NMSS Junior Investigator Award Presentation

 

10:05 am Break

 

10:25 am Human Foxp3+ Regulatory T cells: From Function to Apoptosis

Elisabeth Suri-Payer

 

11:05 am CD39+ Treg cells: Extracellular ATP and Immune Suppression

Olaf Rötzschke

 

11:45 am NMSS Junior Investigator Award Presentation

 

11:50 am Lunch

 

Session IV – Role of Tregs and Th17 Cells in Autoimmune Disease Session

Chair, Joan Goverman

 

1:00 pm Mechanisms for Targeting Inflammation in the CNS by TH17 and TH1 cells

Joan Goverman

 

1:40 pm Regulation of Susceptibility/Resistance to the Theiler's Virus-Induced Demyelinating Disease Model of MS by CD4+ CD25+ Regulatory T Cells

Stephen Miller

 

2:20 pm Break

 

2:40 pm Tregs and T-effectors in CNS Autoimmune Disease

Stephen Anderton

 

3:20 pm Brain Autoimmune T Cells and Their Milieus 

Harmut Wekerle

 

4:00 pm KEYNOTE LECTURE T Cell Differentiation, Migration and Immune Regulation

Antonio Lanzavecchia

 

5:00 pm Closing Remarks

 

5:10 pm Adjourn

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