From Discovery To Application:

Wednesday, February 1, 2006

 

5:00 - 7:00 pm Registration

 

7:00 - 8:30 pm Welcome Reception

Exhibit Hall

 

Thursday, February 2, 2006

 

7:15 am Breakfast

 

8:15 am Opening Remarks

George Demetri and Joanthan Fletcher

 

Session I - Human Cancer Biology: Target Identification

 

8:30 am Cancer Genome Project

Todd Golub

 

9:15 am Discovering Signaling Targets and Identifying Biomarkers

in Cancer: A Proteomic Approach

Akhilesh Pandey

 

10:00 am Bioinformatics, Mapping Oncogenic Pathways

John Chant

 

10:45 am Break

Exhibit Hall

 

Session II - Drug Discovery, Screening, Development

 

11:00 am Relating Genotype to Phenotype with Small Molecules

Stuart Schreiber

 

11:45 am Drugs and Discovery in Cancer Angiogenesis: VEGF

Trap, VelociGene and VelocImmune

George Yancopoulos

 

12:30 pm Lunch

 

Session III - Diagnostics, Biomarkers, Validation

 

1:30 pm Pathology Validations: Fact and Fiction

Brian Rubin

 

2:15 pm Integrating Pathology in Drug Development

Jeffrey Ross

 

3:00 pm Break

Exhibit Hall

 

3:30 pm Antiangiogenic Therapies

John Heymach

 

4:15 pm Shp2 and Its Binding Proteins in Cancer Biology

Benjamin Neel

 

5:00 pm Presentation of Nancy Ann Hughes Welsh Young

Investigator Award

Thomas James Hughes

 

5:30 pm Poster Reception

 

6:30 pm Dinner and Keynote Address: From Molecular to

Modular Cell Biology

Webster Cavenee

 

Friday, February 3, 2006

 

7:00 am Breakfas

Exhibit Hall

 

Session IV - Stem Cell Biology and Therapeutics

 

8:00 am Origins of Cancer Stem Cells

Leonard Zon

 

8:45 am Cancer Stem Cells, Drug Resistance and New Therapies

Michael Dean

 

9:30 am Stem Cells to Therapeutic Targets in Breast Cancer

Matthew Smalley

 

10:15 am Break

 

Session V - Clinical Development

 

10:45 am Successes and Failures in Drug Development:

Lessons from History

Ben Askew

 

11:30 am EGFR Mutants: Biology and Therapeutic Opportunities

Daniel Haber

 

12:15 pm Cancer Drug Development and Somatic Genetic Alterations

William Sellers

 

1:00 pm Closing Remarks

 

1:15 pm Adjourn