Diagnosis and Therapeutic Discovery in Neuro-Oncology

Friday, October 13, 2006

 

7:15 – 8:00 am Breakfast

8:00am Opening Remarks
Drs. Lau & Bogler

Session I - Genomic and Biomarker Discovery
Session Chair, Oliver Bogler

8:15am Genomic Approaches to Understanding the Molecular Basis of Gliomas

Stanley Nelson

 

8:50 am Molecular Predictors of Response and Survival in Glioblastoma
Kenneth Aldape

9:10am Genomic Profiling in Pediatric Glioma

Kwong-Kwok Wong

 

9:30 am Correlating Genomic Profiles with Clinical Variables in Pediatric Ependymoma

Rebecca Holmes Johnson

 

9:50 am Genetic Markers of Familial Gliomas

Melissa Bondy

 

10:10 am Break

 

Session II - Targeted Therapies

Session Chair, Ching Lau

 

10:30 am Molecularly Targeted Therapies for Gliomas

Ian Pollack

 

11:05 am Ligand-directed Vascular Targeting and Molecular Imaging

Renata Pasqualini and Wadih Arap

 

11:30 am Her2 Targeted Cell Therapy for Meduloblastoma

Stephen M. Gottschalk

 

11:50 am Bone Marrow Derived Mesenchymal Stem Cells as Delivery Vehicles

for Brain Tumors

Frederick F. Lang

 

12:10 pm Targeting Histone Deacetylase and Poly(ADP-ribose) Polymerase

in Medulloblastoma

Jack M. Su

 

12:30 - 1:30 pm Lunch

 

Session III - Mouse Models/Cancer Biology

Session Chair, Oliver Bogler

 

1:30 pm Modeling Brain Tumors in Mice

David H. Gutmann

 

2:05 pm Mouse Models of Medulloblastoma

Ganesh Rao

 

2:25 pm Stemnes Is Only One State of the Cell

Sadhan Majumder

 

2:45 pm Orthotopic Xenograft Model for Pediatric Brain Tumor

Xiao-Nan Li

 

3:05 pm Of Schnooks and Supermodels

John Y.H. Kim

 

3:25 pm Break

 

Session IV - Cancer Stem Cells

Session Chair, Ching Lau

 

3:45 pm The Concept of Cancer Stem Cells: Extraordinary Evidence or

Extraordinary Conclusions?

Robert Bachoo

 

4:20 pm Glioblastoma Derived Cancer Stem Cells: Genetic and Epigenetic

Characteristics and Treatment Response

Howard Colman

 

4:40 pm Targeting the Notch Pathway in Stem-like Medulloblastoma/PNET Cells

Charles G. Eberhart

 

5:00 pm Tie2: Bridging Endothelial-to-Cancer Stem Cell Interactions in Gliomas

Candelaris Gomez-Manzano

 

5:20 pm Closing remarks

 

5:30 - 7:00 pm Reception

Characteristics and Treatment Response